The Cal Poly Mustangs fell in their 16th consecutive game Monday evening at home to UC Irvine, 59-56.
The Mustangs had a 31-27 lead heading into the half.
UC Irvine would respond by outscoring the Mustangs in the second half, 32-25.
A layup with 28 seconds left in the game by Dawson Baker gave the Anteaters a 58-56 lead.
Andre Henry's free throw with nine seconds remaining put the game out of reach, with Camren Pierce and Chance Hunter missing the game-tying three-pointers as time expired.
Ali Koroma led the Mustangs with 15 points.
Camren Pierce led the Mustangs with six rebounds to go with his 14 points.
The Mustangs fall to 7-22 overall, with a 1-16 record in conference play.
Cal Poly will close out the regular season with a home game against UC Davis, on the road at UC San Diego, and at home against UC Riverside.
