One person was killed in a crash on Highway 101 near Los Alamos on Thursday.
The two-vehicle crash happened at about 4:30 p.m. in the northbound lanes.
According to the Santa Barbara County Fire Department, two people also suffered major injuries and two others suffered moderate injuries.
The highway was closed so a helicopter could land and pick up one of the injured patients who was taken to a local hospital.
The other patients, including an infant, were taken to the hospital by ambulance.